Publications

 

Peer-reviewed original research articles

Jin C, Frayssinet P,Pelker R, Cwirka D, Hu B, Vignery A, Eisenbarth SC, Flavell RA. The NLRP3 inflammasome plays a critical role in the pathogenesis of hydroxyapatite- associated arthropathy" 2011 Proc Natl Acad Sci U S A, 2011 August 19. [Epub ahead of print]

Kang H, Chang W, Hurley M, Vignery A, Wu D (2010) Important roles of PI3Kg in osteoclastogenesis and bone homeostasis. Proc Natl Acad Sci USA,2010 Jul 20; 107(29):12901-6. Epub 2010 Jul 2.

Zhang Q, Carlson J, Ke H-Z, Li J, Kim M, Murphy K, Mehta N, Gilligan J, Vignery A (2010) Dramatic increase in cortical thickness induced by femoral marrow ablation followed by a three-month treatment with PTH in rats. J Bone and Mineral Research. 25:1350-1359. Epub 2010 March 1

Carlson, J, Cui W, Zhang Q, Xu X, Mercant F, Bennett, A, Vignery, A (2009) Role of MKP-1 in osteoclasts and bone homeostasis. Am J Pathol. 175(4):1564-73. Epub 2009 Sep 17

Carlson, J, Zhang Q, Bennett, A, Vignery, A (2009) Deletion of Mitogen-activated protein kinase phosphatase 1 modifies the response to mechanical bone marrow ablation in a mouse model. Comparative Medicine 59(3),221-226

Zhang, Q, Cuartas, E, Mehta, N, Gilligan, J, Ke, H-Z, Saltzman, WM, Kotas, M, Ma, M, Rajan, S, Chalouni, C, Carlson, J, Vignery, A (2008) Replacement of bone marrow by bone in rat femurs: the bone bioreactor, Tissue Engineering, 14 (2), 237-246

Cui W, Cuartas E, Ke J, Zhang Q, Einarsson H, Sedgwick JD, Li J, VigneryA (2007) CD200 and its receptor, CD200R, modulate bone mass via the differentiation of osteoclasts, Proceedings of the National Academy of Sciences, USA, 104, 14436-14441

Chen E., Grote E., Mohler W, Vignery A. (2007) Cell-Cell fusion, Febs Letters, 581, 2181-2193

Cui W, Zhang Ke J, Zhang Q, Ke H-Z, Chalouni C, Vignery A (2006) The Intracellular Domain of CD44 Promotes the Fusion of Macrophages, Blood, 107, 796-805

Vignery A, Macrophage Fusion: the Making of Osteoclasts and Giant Cells, J Exp Med, 202, 337-340, 2005

Vignery A, Macrophage Fusion: Are Somatic and Cancer Cells Possible Partners?, Trends in Cell Biology, 15, 188-193, 2005

Li H, Cuartas E, Cui W, Choi Y, Crawford DT, Ke HZ, Kobayashi KS, Flavell RA, Vignery A, IRAK-M Is a Central Regulator of Osteoclast Differentiation and Activation, J Exp Med, 201, 1169-1177, 2005

Vignery, A, La fusion des macrophages:partenaires des cellules somatiques et cancereuses?, Medecine/Sciences, 21, 1070-1075, 2005

van Beek EM, Bühring H-J, Colonna M, Hamaguchi M, Howard CJ, Kasuga M, Liu Y, Matozaki T, Neel B G, Parkos CA, Sano S-I, Vignery A, Vivier E, Wright M, Zawatzky R, and Barclay AN (2005) A nomenclature for Signal Regulatory Protein Family Member, Journal of Immunology, 175, 7788-7789

Lesclous P, Guez D, Baroukh B, Vignery A, Saffar JL, Histamine participates in the early phase of trabecular bone loss in ovariectomized rats, Bone, 34, 91-99, 2004

Buehler J, Chappuis P, Saffar JL, Tsouderos Y, Vignery A., Strontium ranelate inhibits bone resorption while maintaining bone formation in alveolar bone in monkeys (macaca fascicularis), Bone, 29(2), 176-179, 2001

Han X, Sterling H, Chen Y, Saginario C, Brown EJ, Frazier WA, Lindberg FP, Vignery A, CD47, a ligand for MFR, participates in macrophage multinucleation, Journal of Biological Chemistry, 275(48), 37984-37992, 2000

Millet I, Phillips R, Sherwin RS, Ghosh S, Voll RE, Flavell RA, Vignery A, Rincon M, Inhibition of NF-kappaB activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptide, Journal of Biological Chemistry, 275, 15114-15121, 2000

Vignery A, Osteoclasts and giant cells:macrophage-macrophage fusion mechanism, International Journal of Experimental Pathology, 81, 291-304, 2000

Ballica R, Valentijn K, Khachatryan A, Guerder S, Kapadia S, Gundberg C, Gilligan J, Flavell RA, Vignery A, Targeted expression of calcitonin gene-related peptide to osteoblasts increases bone density in mice, Journal of Bone and Mineral Research, 14(7), 1067-74, July 1999

Millet I, McCarthy TL, Vignery A, Regulation of IL-6 production by prostaglandin E2 in fetal rat osteoblasts: role of protein kinase A signaling pathway, Journal of Bone and Mineral Research, 13, 1092-1100, 1998

Saginario C, Sterling H, Beckers C, Kobayashi R-J, Solimena M, Ullu E, Vignery A, MFR, a putative receptor mediating the fusion of macrophages, Molecular and Cellular Biology, 18, 6213-6223, 1998

Sterling H, Saginario C, Vignery A, CD44 occupancy prevents the fusion of macrophages, Journal of Cell Biology, 143, 837-847, 1998

Millet I, Vignery A, The neuropeptide calcitonin gene-related peptide inhibits TNF-alpha but poorly induces IL-6 production by fetal rat osteoblasts, Cytokine, 9(12), 999-1007, December 1997

Valentijn K, Gutow A P, Troiano N, Gundberg C, Gilligan J P, Vignery A, Effects of calcitonin gene-related peptide on bone turnover in ovariectomized rats, Bone, 21(3), 269-74, September 1997

Khachatryan A, Guerder S, Palluault F, Cote G, Solimena M, Valentijn K, Millet I, Flavell R A, Vignery A, Targeted expression of the neuropeptide calcitonin gene-related peptide to beta cells prevents diabetes in NOD mice, Journal of Immunology, 158(3), 1409-16, February 1997

Karine Valentijn, Andrew Gutow, Nancy Troiano, Caren Gundberg, James Gilligan, Agnès Vignery, Effects of calcitonin gene related peptide on bone turnover in ovariectomized rats, Bone, 21, 209-214, 1997

Vignery A, McCarthy T L, The neuropeptide calcitonin gene-related peptide stimulates insulin-like growth factor I production by primary fetal rat osteoblasts, Bone, 18(4), 331-5, April 1996

Saginario C, Qian H Y, Vignery A, Identification of an inducible surface molecule specific to fusing macrophages, Proceedings of the National Academy of Sciences (USA), 92(26), 12210-4, 19 Dec 1995

Vignery A, Bone cell defects in osteogenesis imperfecta, Connective Tissue research, 313, 275-278, 1995

Wang F, Millet I, Bottomly K, Vignery A, Calcitonin gene-related peptide inhibits interleukin 2 production by murine T lymphocytes, Journal of Biological Chemistry, 267(29), 21052-7, 15 Oct 1992

Vignery A, Raymond M J, Qian H Y, Wang F, Rosenzweig S A, Multinucleated rat alveolar macrophages express functional receptors for calcitonin, American Journal of Physiology, 261(6 Pt 2), F1026-32, December 1991

Vignery A, Wang F, Ganz M B, Macrophages express functional receptors for calcitonin-gene-related peptide, Journal of Cellular Physiology, 149(2), 301-6, November 1991

Vignery A, Wang F, Qian H Y, Benz E J Jr, Gilmore-Hebert M, Detection of the Na(+)-K(+)-ATPase alpha 3-isoform in multinucleated macrophages, American Journal of Physiology, 260(5 Pt 2), F704-9, May 1991

Vignery A, Niven-Fairchild T, Shepard M H, Recombinant murine interferon-gamma inhibits the fusion of mouse alveolar macrophages in vitro but stimulates the formation of osteoclastlike cells on implanted syngeneic bone particles in mice in viv, Journal of Bone and Mineral Research, 5(6), 637-44, June 1990

Vignery A, Niven-Fairchild T, Ingbar D H, Caplan M, Polarized distribution of Na+,K+-ATPase in giant cells elicited in vivo and in vitro, Journal of Histochemistry and Cytochemistry, 37(8), 1265-71, August 1989

Vignery A, Macrophage multinucleation is accompanied by the expression of new soluble and membrane antigens in mice, American Journal of Pathology, 135, 565-570, 1989

Lang R, Vignery A, Jensen PS, Fibrogenesis imperfecta ossium with early onset - observations after 20 years of illness, Bone, 7, 237-246, 1986

Baron R, Neff L, Nefussi JR, Tran Van P, Vignery A, Kinetic and cytochemical identification of osteoclast precursors and their differentiation into multi-nucleated osteoclasts, American Journal of Pathology, 122, 363--378, 1986

Horowitz M, Baron R, Mart J, Andreoli M, Vignery A., Osteoclast Activating Factor is Distinct from the Monokine IL-1. 24 (S1) :162-164, 1985, British Journal of Rheumatology, 24(S1), 162-164, 1985

Stewart AF, Hoecker JL, Mallett LE, Segre GV, Amatruda TT, Vignery A, Hypercalcemia in Pheochromocytoma: Evidence for a novel mechanism, Annals of Internal Medicine, 102, 776-779, 1985

Baron R, Tross R, Vignery A., Evidence of sequential remodeling histomorphometry during skeletal maturation, Anatomical Record, 208, 137-145, 1984

Insogna KL, Stewart AS, Vignery AMC, Weir EC, Namnum PA, Baron RE, Kirkwood JM, Deftos LM, Broadus AE, Biochemical and histomorphometric characterization of a rat model for humoral hypercalcemia of malignancy, Endocrinology, 114, 888-896, 1984

Horowitz M, Vignery A, Gershon R, Baron R, T-cells are responsible for osteoclast activating factor (OAF) production in murine spleen cells, Proceedings of the National Academy of Sciences (USA), 81, 2181-2185, 1984

Gewirtz AM, Stewart AF, Vignery A, Hoffman R., Hypercalcemia complicating acute myelogenous leukemia: A syndrome of multiple etiologies, British Journal of Haematology, 54, 133-141, 1983

Baron R, Gertner JM, Lang R, Vignery A., Increased bone turnover with decreased bone formation by osteoblasts in children with Osteogenesis Imperfecta Tarda, Pediatric Research, 17, 204-207, 1983

Rodan S, Insogna KL, Vignery AMC, Stewart AF, Broadus AE, D'Souza SM, Bertolini DR, Mundy GR, Rodan GA, Factors associated with humoral hypercalcemia of malignancy stimulate adenylate cyclase in osteoblastic cells, Journal of Clinical Investigation, 72, 1511-1515, 1983

Tran Van P, Vignery A, Baron R., Cellular kinetics of the bone remodeling sequence in the rat, Anatomical Record, 202, 445-451, 1982

Stewart A, Vignery A, Silvergate A, Ravin N, LiVolsi V, Broadus A, Baron R, Quantitative bone histomorphometry in humoral hypercalcemia of malignancy: Uncoupling of bone cell activity, JCEM, 55(2), 219-227, 1982

Tran Van P, Vignery A, Baron R., An electron microscopic study of the bone remodeling sequence in the rat, Cell Tissue Research, 225, 283-292, 1982

Nefussi JR, Vignery A, Puzas JE, Baron R., Histomorphometry and autoradiography of cultured fetal rat long bones, Anatomical Record, 204, 105-112, 1982

Baron R, Vignery A., Behavior of osteoclasts during a rapid change in their number induced by high doses of parathyroid hormone or calcitonin in intact rats, Metab Bone Dis Rel Res, 2, 339-346, 1981

Lang R, Milkman M, Jensen PS, Vignery A., Chronic treatment of Paget's disease of bone with synthetic human calcitonin, Yale Journal of Biology and Medicine, 54, 355-365, 1981

Vignery A, Baron R., Dynamic histomorphometry of alveolar bone remodeling in the adult rat, Anatomical Record, 196, 191-200, 1980

Puzas E, Vignery A, Rasmussen H., Isolation of specific bone cell types by free-flow electrophoresis, Calcified Tissue International, 27(263-268), 1979

Vignery A, Baron R., The effects of parathyroid hormone on the osteoclastic pool and bone resorption and formation in rat alveolar bone, Calcified Tissue Research, 26, 23-28, 1978

Baron R, Saffar J-L, Vignery A., Alveolar bone remodeling: Normal status and effects of PTX and PTH on the remodeling sequence and the osteoclastic pool, Calcified Tissue Research, 22S, 502-504, 1977

Duflot Vignery A, Etude quantitative des effets de la parathyroidectomie sur le remaniement osseux et la migration physiologique des dents chez le rat, Journal de Biologie Buccale, 3, 337-350, 1975

Reviews and Chapters

1. Baron R, Vignery A. Changes in the osteoclastic pools and the osteoclast nuclei balance after a single injection of salmon calcitonin in the adult rat. 1976  In: Bone Histomorphometry, PJ Meunier, Ed, Lab Armour Montagu France, pp. 147-156

2.  Vignery A, Fournier B, Yovanovitch D, Gouineau S.  Amplitude des mouvements mandibulaires:  Etude statistique réalisée chez 25 enfants ages de 9 a 10 ans. 1976  In: Pédodontie Française, pp. 133-137

3.  Vignery A, Donnadieu P.  Dentinogénèse et Ostéogènese imparfaites. 1979  In: Entretiens de Bichat, Masson, Ed.

4.  Vignery A.  Structure, origine et role des vésicules matricielles dans l'os et le cartilage. 1979  Information Dentaire 61, 23:2041-2050

5.  Baron R, Vignery A, Lang B, LiVolsi V, Broadus A.  Lacunes d'inversion et couplage résorption-formation:  comparaison histomorphométrique entre osteopénie et hyperparathyroidie. 1980  In: L'Ostéoporose, Rasmussen H, Eisinger P, Paeche A.  Eds, pp. 141-149

6.  Baron R, Vignery A, Tran Van P.  The significance of lacunar erosion without osteoclasts on the reversal phase of the remodeling sequence. 1980  Third International Workshop on Bone Histomorphometry.  Metab Bone Dis Rel Res 25:35-40

7.  Baron R, Vignery A, Lang R.  Reversal phase and osteopenia:  defective coupling of resorption to formation in the pathogenesis of osteoporosis. 1981  In: Osteoporosis:  Recent Advances in Pathogeny and Treatment.  DeLuca HF, Parfitt M, et al., Eds. University Park Press, Baltimore, pp 311-320

8.  Tran Van P, Vignery A, Baron R.  The effect of space flight on osteogenesis and dentinogenesis in the mandible of rats. 1981  Suppl I: The effects of space flight on alveolar bone modeling and remodeling in the rat mandible.  In: NASA Technical Memorandum 81289.  Final Reports of U.S. Rat Experiments Flown on the Soviet Satellite Cosmos 1129.  MR Heinrich, KA Souza, Eds.  Ames Research Center, California, pp 307-324

9.  Baron R, Tran Van P, Vignery A.  Local control of bone remodeling: suggested role for receptor mediated endocytosis. 1982  In: Current Advances in Skeletogenesis, Slavkin and Silbermann, Eds, Excerpta Medica, Amsterdam, 123-127

10.  Baron R, Vignery A, Neff L, Silvergate A, Santa Maria A.  Processing of undecalcified bone specimens for bone histomorphometry. 1982  In: Bone Histomorphometry: Techniques and Interpretation.  RR Recker, HM Frost, Eds.  CRC Press, Inc., Boca Raton, FL. pp13-35

11.  Baron R, Vignery A, Horowitz M.  Lymphocytes, macrophages and the regulation of bone remodeling. 1983  In: Bone and Mineral Research.  WA Peck, ed.  Elsevier Science Pub Co.  New York,pp175-243

12.  Broadus AE, Insogna KL, Weir EC, Vignery AMC, Burtis WJ, Godsall JW, Stewart AF.  Malignancy-associated hypercalcemia.  1984  in Endocrinology, Labrie F, Proulx L, eds.  Excerpta Medica, Amsterdam. pp 591-594

13.  Vignery A.  Bone cell defects in osteogenesis imperfecta.  Connective Tissue Res 1995  313:275-278

14.  Vignery A.  Osteoclasts and giant cells: macrophage-macrophage fusion mechanism. 2000 Invited review.  Int J Exp Pathol 81:291-304

15.  Vignery A.  Macrophage fusion: the making of osteoclasts and giant cells. 2005 Invited Commentary, J Exp Med 202: 337-340

16.  Vignery A.  La fusion des macrophages: partenaires des cellules somatiques et cancéreuses? 2005 Médecine/ Sciences (Paris). 21:1070-1075

17.  van den Berg TK, van Beek EM, Buhring HJ, Colonna M, Hamaguchi M, Howard CJ, Kasuga M, Liu Y, Matozaki T, Neel BG, Parkos CA, Sano S, Vignery A, Vivier E, Wright M, Zawatzky R, Barclay AN. A nomenclature for signal regulatory protein family members. 2005  J Immunol. 175(12): 7788-7789

18.  Schipani E, Ferrari S, Datta NS, McCauley LK, Vignery A, Bellido T, Strewler JG, Turner CH, Jiang Y, Seeman E.  Meeting Report from the 28th Annual Meeting of the American Society for Bone and Mineral Research. 2006  BoneKEy-Osteovision. 11:14-50, http://www.bonekey-ibms.org/cgi/content/full/ibmske;3/11/14

19.  Chen E, Grote E, Mohler W, Vignery A.  Membrane Exchange Special Issue: Cell-Cell Fusion.  2007 Invited Minireview. FEBS Lett. 581:2181-2193. Epub 2007 Mar 21.

20.  Vignery, A.  Macrophage fusion: molecular mechanisms.  2008 Methods in Molecular Biology, Cell Fusion. Humana Press 475 pp149-161

21.  Vignery, A.  Methods to fuse macrophages in vitro.  2008 Methods in Molecular Biology, Cell Fusion.  Humana Press 475 pp383-395